

If a turtle is defeated, he is captured by the enemy and it is possible to get him back into the game by rescuing him from where he is held. Defeating enemies gains experience points that allow upgrading of the Shell Kicker attacks. Landing a hit combo and then pressing attack again sends the turtle's weapon spinning and then pressing a direction launches a "Shell Kicker" - an extra powerful move that can knock away an enemy's shield, knock them back, deal extra damage or get the turtle behind the enemy.

Basic moves are simple attacks and blocks. They all use their signature weapons and have a slightly different fighting style and moves.

It is possible to switch between the four turtles at any time. Standing in the turtles' way are various goons, reaching from Foot Clan bots over Mouser droids to Kraang soldiers. New skills or items must be unlocked or found to be able to reach new areas. In typical genre style, only a small part of the world is accessible from the start. The turtles' quest will take them through a huge interconnected world, reaching from the sewers to the streets of New York City, the TCRI building and even Dimension X. The game, which uses 3D polygonal graphics for 2D side-scrolling gameplay, is a combination of "Metroidvania"-style exploration-based platformer and beat'em up. The game sends the four Ninja Turtles out to prevent a canister of super mutagen from falling into the hands of the Shredder and his cronies. Teenage Mutant Ninja Turtles: Danger of the Ooze is based on the 2012 Nickelodeon TV series.
